Medical AI center, Niigata University School of Medicine/Niigata University Graduate School of Medical and Dental Sciences - Medical AI Center/Bioinformatics laboratory

About us

Bioinformatics laboratory focuses on the following topics.

Functional genomics/metagenomics

Human gut microbiomes
Comparative metagenomics
Evolution of phosphorylation
Cancer genomics
Artificial intelligence (machine learning)

Database construction

HEMM: Human - Earth Microbes and Microbiomes
ODB: Operon DataBase
GlycoEpitope
jPOST: Japan ProteOme STandard repository/database.

Latest publications

Ozeki, H., Shimada, Y., Nakano, M., Kondo, S., Ohashi, R., Miwa, Y., Yamai, D., Matsumoto, A., Abe, K., Tajima, Y., Ichikawa, H., Sakata, J., Takii, Y., Sugai, M., Nagai, T., Ling, Y., Okuda, S., Wakai, T. Mucin phenotype and genetic alterations in non-V600E BRAF-mutated colorectal cancer. Hum. Pathol. 145:71-79(2024). PubMed Human Pathology
Paper
Takahashi, K., Yachida, N., Tamura, R., Adachi, S., Kondo, S., Abé, T., Umezu, H., Nyuzuki, H., Okuda, S., Nakaoka, H., Yoshihara, K. Clonal origin and genomic diversity in Lynch syndrome-associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H. Genes Chromosomes Cancer 63(3):e23231(2024). PubMed Genes Chromosomes Cancer
Paper
Takeuchi, Y., Sato, S., Nagasato, C., Motomura, T., Okuda, S., Kasahara, M., Takahashi, F., Yoshikawa, S. Sperm-specific histone H1 in highly condensed sperm nucleus of Sargassum horneri. Sci. Rep. 14(1):3387(2024). PubMed scientific reports
Paper
Hesham, D., On, J., Alshahaby, N., Amer, N., Magdeldin, S., Okada, M., Tsukamoto, Y., Hiraishi, T., Imai, C., Okuda, S., Wakai, T., Kakita, A., Oishi, M., El-Naggar, S., Natsumeda, M. Multi-omics analyses of choroid plexus carcinoma cell lines reveal potential targetable pathways and alterations. J. Neurooncol. 166(1):27-38(2024). PubMed Journal of Neuro-Oncology
Paper
Yamai, D., Shimada, Y., Nakano, M., Ozeki, H., Matsumoto, A., Abe, K., Tajima, Y., Nakano, M., Ichikawa, H., Sakata, J., Nagai, T., Ling, Y., Okuda, S., Watanabe, G., Nogami, H., Maruyama, S., Takii, Y., Wakai, T. Clinical significance of metastatic tumor deposit foci in rectal cancer in the lateral pelvic lymph node area. Int. J. Clin. Oncol. 28(10):1388-1397(2023). PubMed International Journal of Cl …
Paper
Kobayashi, E., Ling, Y., Kobayashi, R., Hoshikawa, E., Itai, E., Sakata, O., Okuda, S., Naru, E., Isumi, K. Development of a lip vermilion epithelium reconstruction model using keratinocytes from skin and oral mucosa. Histochem. Cell Biol. 160(4):349‐359(2023). PubMed Histochemistry cell biology
Paper

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