NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma.
Murayama,Y., Kasahara, Y., Kubo, N., Shin, C., Imamura,M., Oike, N., Ariizumi, T., Saitoh, A., Baba, M., Miyazaki, T., Suzuki, Y., Ling, Y., Okuda, S., Mihara, K., Ogose, A., Kawashima, H., Imai, C. NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma. Transl. Oncol. 25:101521(2022).
Elevated bile acid metabolism and microbiome are associated with suppressed cell proliferation and better survival in breast cancer.
Wu, R., Yu, I., Tokumaru, Y., Asaoka, M., Oshi, M., Yan, L., Okuda, S., Ishikawa, T., Takabe, K. Elevated bile acid metabolism and microbiome are associated with suppressed cell proliferation and better survival in breast cancer. Am. J. Cancer Res. 12(11):5271-5285(2022).
Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients.
Tajima, Y., Okuda, S., Hanai, T., Hiro, J., Masumori, K., Koide, Y., Kamiya, T., Cheong, Y., Inaguma, G., Shimada, Y., Wakai, T., Takihara, H., Akimoto, S., Matsuoka, H., Uyama, I., Suda, K. Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients. Sci. Rep. 12(1)18193(2022).
Gene panel testing detects important genetic alterations in ulcerative colitis-associated colorectal neoplasia.
Shimada, Y., Nakano, M., Mizuno, K. I., Yokoyama, J., Matsumoto, A., Tanaka, K., Oyanagi, H., Nakano, M., Hirose, Y., Ichikawa, H., Sakata, J., Kameyama, H., Takii, Y., Sugi, M., Ling, Y., Takeuchi, S., Okuda, S., Terai, S., Ajioka, Y., Wakai, T. Gene panel testing detects important genetic alterations in ulcerative colitis-associated colorectal neoplasia. Oncol. Lett. 24(6):442(2022).
Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Yoshida, Y., Shimizu, I., Shimada, A., Nakahara, K., Yanagisawa, S., Kubo, M., Fukuda, S., Ishii, C., Yamamoto, H., Ishikawa, T., Kano, K., Aoki, J., Katsuumi, G., Suda, M., Ozaki, K., Yoshida, Y., Okuda, S., Ohta, S., Okamoto, S., Minokoshi, Y., Oda, K., Sasaoka, T., Abe, M., Sakimura, K., Kubota, Y., Yoshimura, N., Kajimura, S., Zuriaga, M., Walsh, K., Soga, T., Minamino, T. Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci. Rep. 12(1):14883(2022).
Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy.
Yoshioka, N., Kurose, M., Yano, M., Tran, D. M., Okuda, S., Mori-Ochiai, Y., Horie, M., Nagai, T., Nishino, I., Shibata, S., Takebayashi, H. Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy. Elife 11:e78419(2022).
Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity.
Hayashi, Y., Shimizu, I., Yoshida, Y., Ikegami, R., Suda, M., Katsuumi, G., Fujiki, S., Ozaki, K., Abe, M., Sakimura, K., Okuda, S., Hayano, T., Nakamura, K., Walsh, K., Jespersen, N. Z., Nielsen, S., Scheele, C., Minamino, T. Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity. iScience 25(7):104547(2022).
Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer.
Okuda, S., Hirose, Y., Takihara, H., Okuda, A., Ling, Y., Tajima, Y., Shimada, Y., Ichikawa, H., Takizawa, K., Sakata, J., Wakai, T. Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer. Sci. Rep. 12(1):8766(2022).
Efficacy of BRAF inhibitor and anti-EGFR antibody in colorectal neuroendocrine carcinoma.
Nakano, M., Shimada, Y., Matsumoto, Y., Saiki, T., Zhou, Q., Sasaki, K., Moriyama, M., Yoshihara, K., Natsumeda, M., Kuriyama, Y., Takii, Y., Watanabe, G., Umezu, H., Okuda, S., Ikeuchi, T., Wakai, T., Saijo, Y. Efficacy of BRAF inhibitor and anti-EGFR antibody in colorectal neuroendocrine carcinoma. Clin. J. Gastroenterol. 15(2):413-418(2022).
Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells.
Suda, M., Shimizu, I., Katsuumi, G., Hsiao, C. L., Yoshida, Y., Matsumoto, N., Yoshida, Y., Katayama, A., Wada, J., Seki, M., Suzuki, Y., Okuda, S., Ozaki, K., Nakanishi-Matsui, M., Minamino, T. Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells. Sci. Rep. 12(1):6522(2022).